The Science of Secretome

What your follicles release, your scalp can use

Stem cells communicate through the signals they secrete. Cultivated from your own banked cells, Secretome brings three regenerative messengers together in one personalized scalp therapy.

Personalized secretome by Acorn

MicrovesiclesMedium extracellular vesicles

Larger carriers with exosome-like cargo plus membrane and modified proteins that support cell-to-cell communication.

ExosomesSmall extracellular vesicles

Tiny messengers carrying proteins, lipids, enzymes and genetic signals (DNA, mRNA and miRNA) that guide how the cells around each follicle behave.

Soluble FactorsFree-floating signals

Growth factors, cytokines, chemokines, proteins and enzymes that support the follicle environment, renewal and repair.

SecretomeAll three, combined

Your complete regenerative signal, cultivated from your own cells into a treatment made only for you.

Why hair thins

Follicles slow down. They don’t stop.

Hair thins as follicles spend less time growing and gradually shrink — and as cells age, they send fewer of the regenerative signals follicles rely on. At 65, your cells still make every regenerative signal they made at 35, just less of it. Over about 60 days, Acorn collects and concentrates what your cells release into your personal Secretome, offsetting about 85% of the loss across a 30-year age difference.

Dr. Drew Taylor · CEO, Acorn Biolabs, on Skin Anarchy

The gap 30 years creates100%

Offset by your Secretome

~85% offset~15% remains

60days to your concentrated Secretome

87years: Acorn’s oldest reported results

100%your own cells

Your Secretome Journey

From collection to renewal

One quick visit starts it all. About two months later, your own Secretome is ready to apply — and your bank remains on reserve for the future.

Day 0
Collection
About 50 follicles are gently collected at Nude Medical Aesthetics — no scalpels, stitches or downtime. Back to your day in minutes.
Day 1
The process begins
Your live cells arrive at the Acorn lab, are tested for viability and banked at −196°C. A portion begins cultivation, where what your cells release is collected and concentrated over the following weeks into your personal Secretome. If a sample falls short, recollection is free.
Day 60
Your Secretome is ready
Your concentrated blend of exosomes, growth factors and regenerative proteins returns to Nude Medical Aesthetics, ready for application.
Treatment
The Nude Medical Aesthetics protocol
Delivered to the scalp with Exceed® Medical Microneedling and TargetCool® to carry your Secretome to the follicle environment.

The Nude Medical Aesthetics Secretome Protocol

Your cells, delivered with precision

01

Exceed^® Medical Microneedling

German-engineered and the first medical microneedling device FDA-cleared for both facial wrinkles and acne scars. On the scalp, precise micro-channels open a direct pathway for your Secretome to reach the follicle environment.

02

TargetCool^®

FDA-cleared precision CO₂ cooling. A controlled supersonic CO₂ stream helps carry your Secretome into the scalp while calming redness, swelling and discomfort.

03

The Bohr Effect

CO₂ delivered to the scalp lowers local pH, prompting hemoglobin to release more oxygen into surrounding tissue — supporting the scalp environment where healthy hair grows.

The resultYour own regenerative signals, delivered to a scalp primed with oxygen — for hair restoration that is uniquely yours.

The Nude Regenerative Ritual™

Your cells, banked. Your Secretome, delivered.

Everything you need to begin, in one ritual — no consultation required.

$4,750BENUDE® member price $3,800Storage renews at $190 per year after the first year.

Collection of about 50 hair follicles at Nude Medical Aesthetics
Cultivation of your personal YOU™ Secretome
One year of cryogenic cell storage at −196°C
Three Exceed^® Medical Microneedling sessions with your YOU™ Secretome and TargetCool^®

Purchase the Ritual Or book a consultation first

Your Secretome is ready about 60 days after collection. Candidacy is confirmed by your provider.

And this is only the beginning. The future holds so much more.

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